CARI Guidelines aims to improve the quality of care and outcomes for patients with kidney disease in Australia & New Zealand. They develop and implement clinical practice guidelines based on the best available evidence. Guidelines have been produced on a wide range of topics such as blood pressure targets and lifestyle modifications to prevent disease progression. Clinical practice guidelines have proved enormously valuable; adherence to the recommendations contained within them translates directly into benefits for patients, practitioners and providers through improved outcomes, better quality of care and improved cost-effectiveness. CARI Guidelines is an externally funded research program within the University of Sydney and is supported by the Australia and New Zealand Society of Nephrology and Kidney Health Australia.